Professor of Immunology, Hannover Medical School, Hannover, Germany
Reinhard Schwinzer is transplant immunologist and head of the Transplant
Laboratory of the Clinic for General-, Visceral-, and Transplantation Surgery at Hannover Medical School, Germany.
He received his MSc degree (1983) in biology from the Technical University of Braunschweig, Germany, and his PhD degree in biology (1987) from the Leibniz University, Hannover, Germany. He was a Postdoctoral fellow of the German Research Foundation (DFG) at National Jewish Centre for Immunology, Denver, Co. USA. After coming back to Hannover (1991), he established a research group in the Transplant Laboratory and became head of the Lab in 2007.
His major research interest is the analysis of mechanisms regulating T cell activation, focusing on the role of co-stimulatory and –inhibitory molecules. He developed concepts to decrease human anti-pig immune responses by enhancing inhibitory signals in human T cells. Reinhard Schwinzer and his team were first who described polymorphisms in the human cell surface molecules CD45 and CD161. The question as to how this genetic variability influences the individual’s immune reactivity to alloand xenografts is another research focus of the group.